Description

[6-(Difluoromethyl)-3-Pyridyl]Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring a difluoromethyl group and a hydroxymethyl arm, makes it an essential intermediate for creating novel compounds with tailored properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the difluoromethyl group for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic processes.
• Material Science Research: Intermediate for synthesizing fluorinated polymers or liquid crystals with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	[6-(Difluoromethyl)-3-Pyridyl]Methanol
CAS No.	946578-33-2
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	(6-(Difluoromethyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 6-(difluoromethyl)-; 6-(Difluoromethyl)pyridine-3-methanol; 5-(Hydroxymethyl)-2-(difluoromethyl)pyridine; 2-(Difluoromethyl)-5-(hydroxymethyl)pyridine
EINECS	Contact for details

Quality Control

Our production of [6-(Difluoromethyl)-3-Pyridyl]Methanol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and sources of fluoride ions. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.