Description

Cefdinir Lactone CAS NO 946573-41-7 is a key pharmaceutical intermediate in the synthesis of the third-generation oral cephalosporin antibiotic, Cefdinir. This high-purity compound is critical for ensuring the final API meets stringent pharmacopeial standards for purity, potency, and safety. It is primarily required by manufacturers in the pharmaceutical and fine chemical industries engaged in advanced antibiotic production and research.

Application

• Primary Intermediate in the commercial synthesis of the active pharmaceutical ingredient (API) Cefdinir.
• Research & Development for novel cephalosporin derivatives and next-generation β-lactam antibiotics.
• Process Chemistry optimization and scale-up studies within pharmaceutical manufacturing.
• Quality Control Reference Standard for analytical method development and validation in API production.
• Fine Chemical Synthesis for specialized chemical building blocks requiring a β-lactam structure.

Basic Information

Product Name	Cefdinir Lactone
CAS No.	946573-41-7
Molecular Formula	C14H13N5O5S2
Molecular Weight	395.41 g/mol
Synonyms	(6R,7R)-7-[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-hydroxyiminoacetamido]-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Lactone; Cefdinir δ2-Isomer; Cefdinir Lactone Form; Cefdinir Impurity; Cefdinir Intermediate; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our Cefdinir Lactone is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical intermediate use, with typical purity exceeding 98.0% (by HPLC). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.