Description

Ly2409881 Trihydrochloride is a high-purity, non-peptidic small molecule compound designed for advanced research and development. This compound is a critical tool for scientists investigating specific biological pathways and therapeutic targets. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on preclinical discovery and mechanism-of-action studies.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and optimization of novel therapeutic agents.
• Biochemical Assay Development: Used as a precise molecular tool to validate assay systems, study enzyme kinetics, and screen for potential inhibitors or activators in high-throughput settings.
• Preclinical In Vitro Studies: Essential for conducting cell-based experiments to evaluate compound efficacy, potency, and selectivity against specific biological targets.
• Mechanism of Action (MoA) Research: Employed to elucidate detailed signaling pathways and understand the pharmacodynamic profile of related chemical entities.
• Analytical Method Development: Acts as a certified reference material for calibrating analytical instruments such as HPLC and LC-MS, ensuring accurate quantification in complex matrices.

Basic Information

Product Name	Ly2409881 Trihydrochloride
CAS No.	946518-60-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LY-2409881 trihydrochloride; LY2409881 HCl; 946518-60-1; LY 2409881; (3S,4R)-3-[[(3S)-3-(4-chlorophenyl)-4,5-dihydro-5-isoxazolyl]methyl]-1-(2,4-difluorophenyl)-4-[(4-fluorophenyl)methyl]-2-pyrrolidinone trihydrochloride (IUPAC); LY2409881 (free base)
EINECS	Contact for details

Quality Control

Our Ly2409881 Trihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC. A detailed Certificate of Analysis (COA) documenting the results for identity, assay, purity, and residual solvents is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Total impurities ≤ 1.0%)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.