Description

4-Methoxy-3-Pyridinesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative used as a key building block in organic synthesis. Its primary value lies in its ability to introduce the 4-methoxy-3-pyridinesulfonyl moiety, a crucial functional group for modulating the physicochemical and biological properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, where the sulfonamide linkage enhances bioactivity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling proteins or synthesizing activity-based probes (ABPs) due to its sulfonyl chloride group.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a substituted pyridinesulfonyl group.

Basic Information

Product Name	4-Methoxy-3-Pyridinesulfonyl Chloride
CAS No.	945257-53-4
Molecular Formula	C6H6ClNO3S
Molecular Weight	207.63 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 4-methoxy-; 4-Methoxy-3-pyridinesulfonyl chloride; 4-Methoxypyridine-3-sulfonyl chloride; 3-(Chlorosulfonyl)-4-methoxypyridine; 4-Methoxy-pyridine-3-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-Pyridinesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.