Description

Crac Inhibitor 44 is a specialized chemical compound designed to effectively modulate calcium release-activated calcium (CRAC) channels. This product is critical for research and development in cellular signaling pathways, offering a targeted mechanism of action. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in immunology, neurology, and cardiovascular disease studies.

Application

• Pharmacological Research: As a selective CRAC channel inhibitor for studying calcium signaling in immune cells (e.g., T-cells, mast cells).
• Drug Discovery: A key reference compound or starting material in the development of novel therapeutics for autoimmune disorders and inflammatory diseases.
• Academic & Biomedical Research: For in vitro and ex vivo studies to elucidate the role of CRAC channels in various physiological and pathological processes.
• Biochemical Assay Development: Used as a standard or control agent in high-throughput screening (HTS) campaigns and functional cellular assays.
• Target Validation: Essential tool for confirming the biological role of specific ion channels in disease models.

Basic Information

Product Name	Crac Inhibitor 44
CAS No.	944917-72-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CRAC Channel Inhibitor 44; 2-Aminoethoxydiphenyl Borate (2-APB) analog; Calcium Release-Activated Calcium Channel Blocker 44; SOCE Inhibitor; ORAI Channel Inhibitor; STIM/ORAI Interaction Inhibitor; Research Compound 944917-72-0; BTP-2 related compound
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade standards. Identity and purity are confirmed using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation (NMR, MS), and impurity profile is provided with each shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.