Description

1-(5-(Trifluoromethyl)-2-Methoxypyridin-3-Yl)Ethanone is a high-value trifluoromethylated pyridine derivative, a key building block prized for its ability to impart metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists working on novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its primary demand originates from the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop products with enhanced efficacy and patent life.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(5-(Trifluoromethyl)-2-Methoxypyridin-3-Yl)Ethanone
CAS No.	944900-51-0
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	3-Acetyl-5-(trifluoromethyl)-2-methoxypyridine; 1-[5-(Trifluoromethyl)-2-methoxypyridin-3-yl]ethanone; 2-Methoxy-5-(trifluoromethyl)pyridin-3-yl methyl ketone; Ethanone, 1-[5-(trifluoromethyl)-2-methoxy-3-pyridinyl]-; 3-Acetyl-2-methoxy-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-(Trifluoromethyl)-2-Methoxypyridin-3-Yl)Ethanone is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment ensures batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.