Description

(2E)-3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propenoic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a propenoic acid moiety and a trifluoromethyl-substituted pyridine ring, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams within the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functional organic materials, such as liquid crystals or organic semiconductors, due to its conjugated system and fluorine content.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	(2E)-3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propenoic Acid
CAS No.	944805-93-0
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	(E)-3-(6-(Trifluoromethyl)pyridin-3-yl)acrylic acid; trans-3-[6-(Trifluoromethyl)-3-pyridyl]propenoic acid; 3-(6-(Trifluoromethyl)pyridin-3-yl)acrylic acid; 2-Propenoic acid, 3-[6-(trifluoromethyl)-3-pyridinyl]-, (2E)-; 5-(2-Carboxyvinyl)-2-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our (2E)-3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propenoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.