Description

2-Fluoro-4-Methylpyridine-5-Carboxylic Acid is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its role in introducing both fluorine and a carboxylic acid functional group into complex molecular architectures, enabling precise modulation of physical and biological properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that require specific fluorinated aromatic components.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Fluoro-4-Methylpyridine-5-Carboxylic Acid
CAS No.	944582-95-0
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Carboxy-2-fluoro-4-methylpyridine; 4-Methyl-2-fluoropyridine-5-carboxylic Acid; 2-Fluoro-4-picoline-5-carboxylic Acid; 2-Fluoro-4-methyl-5-pyridinecarboxylic Acid; 944582-95-0; 2-Fluoro-4-methylpyridine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methylpyridine-5-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods (HPLC, NMR) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.