Description

2-Bromo-6-Methylbenzotrifluoride is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi), enabling the rapid construction of diverse biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating specialty polymers, ligands for catalysis, and advanced organic frameworks.

Basic Information

Product Name	2-Bromo-6-Methylbenzotrifluoride
CAS No.	944268-56-8
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-2-methyl-3-(trifluoromethyl)benzene; 2-Methyl-6-(trifluoromethyl)bromobenzene; 2-Bromo-α,α,α-trifluoro-o-xylene; 2-Bromo-6-(trifluoromethyl)toluene; o-Bromo-α,α,α-trifluoro-m-xylene; (2-Bromo-6-methylphenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.