Description

4-(2,7-Dioxo-[1,3]Diazepan-1-Yl)-Benzenesulfonyl Chloride is a specialized heterocyclic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, enabling the precise construction of complex molecules for pharmaceutical and agrochemical research. This high-purity intermediate is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the development of protease inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially protease inhibitors and enzyme-targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced active ingredients for crop protection products.
• Bioconjugation & Probe Development: Acts as a reactive handle for labeling biomolecules or creating chemical probes for biochemical assays.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with specific functional properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-fidelity building blocks.

Basic Information

Product Name	4-(2,7-Dioxo-[1,3]Diazepan-1-Yl)-Benzenesulfonyl Chloride
CAS No.	942474-16-0
Molecular Formula	C11H11ClN2O4S
Molecular Weight	302.73 g/mol
Synonyms	1-[4-(Chlorosulfonyl)phenyl]-1,3-diazepane-2,7-dione; 4-(2,7-Dioxo-1,3-diazepan-1-yl)benzenesulfonyl chloride; Benzenesulfonyl chloride, 4-(2,7-dioxo-1H-1,3-diazepan-1-yl)-; 942474-16-0; 4-(2,7-Dioxo-[1,3]diazepan-1-yl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-(2,7-Dioxo-[1,3]Diazepan-1-Yl)-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided with every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.