Description

3',4'-Dimethoxy-Biphenyl-3-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its role as a versatile electrophilic reagent for introducing the sulfonyl functional group, enabling the creation of complex molecules with tailored properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the sulfonamide moiety can contribute to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.

Basic Information

Product Name	3',4'-Dimethoxy-Biphenyl-3-Sulfonyl Chloride
CAS No.	942473-58-7
Molecular Formula	C14H13ClO4S
Molecular Weight	312.77 g/mol
Synonyms	3-(3,4-Dimethoxyphenyl)benzenesulfonyl chloride; 3',4'-Dimethoxy[1,1'-biphenyl]-3-sulfonyl chloride; 3,4-Dimethoxybiphenyl-3'-sulfonyl chloride; Biphenyl-3-sulfonyl chloride, 3',4'-dimethoxy-; (3',4'-Dimethoxybiphenyl-3-yl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3',4'-Dimethoxy-Biphenyl-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.