Description

2-Chloro-5-Cyanobenzene-1-Sulfonyl Chloride is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a sulfonyl chloride and a nitrile group, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with sulfonylurea or sulfonamide moieties.
• Functional Material Development: Serves as a monomer or cross-linking agent in the production of specialty polymers and high-performance resins.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex organic dyes and colorants.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating compound libraries for screening.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal complexes and catalysts.

Basic Information

Product Name	2-Chloro-5-Cyanobenzene-1-Sulfonyl Chloride
CAS No.	942199-56-6
Molecular Formula	C7H3Cl2NO2S
Molecular Weight	236.07 g/mol
Synonyms	2-Chloro-5-cyanobenzenesulfonyl chloride; 3-Chloro-4-cyanobenzenesulfonyl chloride; 4-Cyano-3-chlorobenzenesulfonyl chloride; 1-Chloro-2-cyano-4-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 2-chloro-5-cyano-; 942199-56-6; 2-Chloro-5-cyanophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-Cyanobenzene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF Titration)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.