Description

1-Methyl-1H-Indole-7-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, essential for introducing the 1-methylindole-7-sulfonyl moiety into target molecules. Its core value lies in its role as a key synthetic intermediate, enabling the construction of complex chemical architectures with precision. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the indole sulfonamide structure can confer specific biological activity.
• Organic Synthesis Reagent: Serves as a versatile reagent for sulfonamide coupling reactions, facilitating the creation of sulfonamide libraries for high-throughput screening.
• Material Science Research: Employed in the development of advanced organic materials, such as polymers or liquid crystals, where its functional groups can modify material properties.
• Bioconjugation Chemistry: Potentially useful for modifying biomolecules (e.g., peptides, proteins) by reacting with amine groups to form stable sulfonamide linkages.

Basic Information

Product Name	1-Methyl-1H-Indole-7-Sulfonyl Chloride
CAS No.	941716-95-6
Molecular Formula	C9H8ClNO2S
Molecular Weight	229.68 g/mol
Synonyms	1-Methyl-7-indolesulfonyl chloride; 1-Methyl-1H-indole-7-sulfonyl chloride; 7-(Chlorosulfonyl)-1-methyl-1H-indole; 1-Methylindole-7-sulfonyl chloride; N-Methylindole-7-sulfonyl chloride; 1-Methyl-7-sulfonylchloride indole; 1H-Indole-7-sulfonyl chloride, 1-methyl-
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Indole-7-Sulfonyl Chloride is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, it should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Recommended storage temperature is 2-8°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.