Description

3-Bromo-5-Chloro-2-Fluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core provides bioactivity.
• Material Science Precursor: Serves as a starting material for synthesizing functionalized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: The bromine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: Used in nucleophilic aromatic substitution reactions, leveraging the fluorine atom for further derivatization.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	3-Bromo-5-Chloro-2-Fluoropyridine
CAS No.	937379-60-7
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	2-Fluoro-3-bromo-5-chloropyridine; 5-Chloro-3-bromo-2-fluoropyridine; 3-Bromo-5-chloro-2-fluoro-pyridine; Pyridine, 3-bromo-5-chloro-2-fluoro-; 937379-60-7; 2-Fluoro-3,5-dihalopyridine; BCFFP
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-2-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.