Description

6-Bromo-2-Fluoropyridin is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for introducing functional complexity into target molecules. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and organometallic catalysts.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	6-Bromo-2-Fluoropyridin
CAS No.	937379-49-2
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	2-Fluoro-6-bromopyridine; 6-Bromo-2-fluoropyridine; 2-Bromo-6-fluoropyridine; 6-Bromo-2-fluoro-pyridine; Pyridine, 6-bromo-2-fluoro-; 2-Fluoropyridine, 6-bromo-; 6-Br-2-F-Py; 2-F-6-Br-Py
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoropyridin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ICH Q7 guidelines, and relevant global regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.