Description

4-Trifluoromethyl-Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its pyridine core, nitrile group, and trifluoromethyl substituent. This compound matters for its role in facilitating efficient molecular construction, particularly in the synthesis of complex agrochemicals and pharmaceuticals where the CF3 group is a critical pharmacophore. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and advanced material sectors seeking to introduce fluorine-containing motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyridine-based ligands used in catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as electron-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Trifluoromethyl-Pyridine-2-Carbonitrile
CAS No.	936841-69-9
Molecular Formula	C7H3F3N2
Molecular Weight	172.11 g/mol
Synonyms	2-Cyano-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)picolinonitrile; 4-(Trifluoromethyl)-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 4-(trifluoromethyl)-; 4-Trifluoromethyl-2-cyanopyridine; α,α,α-Trifluoro-p-picolinonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Trifluoromethyl-Pyridine-2-Carbonitrile is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.