Description

n-(5-Chloro-2-Pyridinyl)-2-[[4-[(Dimethylamino)Iminomethyl]Benzoyl]Amino]-5-Methoxybenzamide (2Z)-2-Butenedioate (1:1) is a high-purity, non-racemic organic salt compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or active pharmaceutical ingredient (API) for the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of complex, target-specific molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and targeted therapy research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for the development and scale-up of new chemical entities (NCEs).
• Biochemical Research: Used in life science research for studying enzyme inhibition, receptor binding, and other molecular interactions.
• Process Chemistry & Scale-Up: Employed in process development and optimization for the commercial manufacturing of complex pharmaceuticals.
• Reference Standard: Sourced for use as an analytical reference standard in quality control (QC) and method development laboratories.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary derivatives and analogs.

Basic Information

Product Name	n-(5-Chloro-2-Pyridinyl)-2-[[4-[(Dimethylamino)Iminomethyl]Benzoyl]Amino]-5-Methoxybenzamide (2Z)-2-Butenedioate (1:1)
CAS No.	936539-80-9
Molecular Formula	C27H27ClN6O5 • C4H4O4
Molecular Weight	Contact for details
Synonyms	5-Chloro-N-(2-((4-((dimethylamino)methyl)benzoyl)amino)-5-methoxyphenyl)-2-pyridinecarboxamide fumarate; (Z)-But-2-enedioic acid; compound with 5-chloro-N-[2-[[4-[(dimethylamino)methyl]benzoyl]amino]-5-methoxyphenyl]pyridine-2-carboxamide (1:1); Fumarate salt of a pyridinecarboxamide derivative; Pharmaceutical intermediate 936539-80-9; Research chemical 936539-80-9; API intermediate CAS 936539-80-9
EINECS	Contact for details

Quality Control

Our n-(5-Chloro-2-Pyridinyl)-2-[[4-[(Dimethylamino)Iminomethyl]Benzoyl]Amino]-5-Methoxybenzamide (2Z)-2-Butenedioate (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.