Description

Bix 01294, 2-(Hexahydro-4-Methyl-1H-1,4-Diazepin-1-Yl)-6,7-Dimethoxy-n-[1-(Phenylmethyl)-4-Piperidinyl]-4-Quinazolinamine Hydrate Trihydrochloride is a high-purity, complex organic compound supplied as a trihydrochloride salt hydrate. This compound is a critical pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry and drug discovery programs. It is primarily utilized by pharmaceutical R&D organizations and contract research organizations (CROs) for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in biochemical and cellular assays to study and develop inhibitors for various kinase targets.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed as a tool compound in academic and industrial research to investigate cellular signaling mechanisms.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	Bix 01294, 2-(Hexahydro-4-Methyl-1H-1,4-Diazepin-1-Yl)-6,7-Dimethoxy-n-[1-(Phenylmethyl)-4-Piperidinyl]-4-Quinazolinamine Hydrate Trihydrochloride
CAS No.	935693-62-2
Molecular Formula	C34H48Cl3N7O3 • xH2O
Molecular Weight	Contact for details
Synonyms	Bix 01294; Bix-01294; Bix01294; 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[1-(phenylmethyl)-4-piperidinyl]-6,7-dimethoxy-4-quinazolinamine trihydrochloride hydrate; G9a Histone Methyltransferase Inhibitor BIX-01294; UNII-8JQ5607E5F; BIX 01294 trihydrochloride hydrate; 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)piperidin-4-yl]quinazolin-4-amine trihydrochloride hydrate
EINECS	Contact for details

Quality Control

Our Bix 01294 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Contact for details
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.