Description

5-Fluoropyrimidine-2-Carbaldehyde is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive aldehyde group and fluorinated heterocyclic core, which are essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated nucleoside analogs and other potential therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the fluoropyrimidine scaffold for enhanced activity.
• Chemical Biology & Medicinal Chemistry: Employed as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and advanced organic materials.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions for constructing complex heterocyclic systems.
• Ligand Synthesis: Utilized for preparing novel chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Fluoropyrimidine-2-Carbaldehyde
CAS No.	935667-50-8
Molecular Formula	C5H3FN2O
Molecular Weight	126.09 g/mol
Synonyms	2-Formyl-5-fluoropyrimidine; 5-Fluoro-2-pyrimidinecarboxaldehyde; 5-Fluoropyrimidine-2-carboxaldehyde; 5-Fluoro-2-formylpyrimidine; 2-Pyrimidinecarboxaldehyde, 5-fluoro-; 935667-50-8; 5-Fluoropyrimidinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoropyrimidine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.