Description

Linzagolix is a non-peptide, orally active gonadotropin-releasing hormone (GnRH) receptor antagonist. This compound is a critical active pharmaceutical ingredient (API) for developing targeted hormonal therapies. It is primarily utilized in the pharmaceutical industry for the research and production of treatments for hormone-dependent conditions such as endometriosis and uterine fibroids.

Application

• Active Pharmaceutical Ingredient (API) for the manufacture of GnRH antagonist drugs.
• Research and development of novel therapeutics for endometriosis management.
• Development of non-surgical treatment options for uterine fibroids (leiomyomas).
• Clinical research into hormone-dependent reproductive system disorders.
• Preclinical studies investigating mechanisms of GnRH receptor blockade.
• Formulation development for oral dosage forms in pharmaceutical manufacturing.

Basic Information

Product Name	Linzagolix
CAS No.	935283-04-8
Molecular Formula	C29H30F3N5O3
Molecular Weight	553.58 g/mol
Synonyms	Linzagolix; OBE2109; KLH-2109; 4-[[(1R)-1-[2-(2,6-Difluorophenyl)acetyl]-2-(4-fluorophenyl)-4-(4-morpholinyl)-1,2,3,4-tetrahydro-6-quinolinyl]methyl]-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5(4H)-one; 1-(2,2,2-Trifluoroethyl)-4-[[(1R)-1-[2-(2,6-difluorophenyl)acetyl]-2-(4-fluorophenyl)-4-(4-morpholinyl)-1,2,3,4-tetrahydro-6-quinolinyl]methyl]-1,2,4-triazol-5-one
EINECS	Contact for details

Quality Control

Our Linzagolix is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical-grade active ingredients. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.