Description

2-Butoxy-3,4-Difluorobenzenamine is a specialized aromatic amine derivative featuring both fluorine and alkoxy substituents, making it a valuable intermediate in advanced chemical synthesis. Its molecular structure is engineered to impart specific electronic and steric properties, which are critical for developing high-performance materials and active pharmaceutical ingredients. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce difluorinated aniline motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoro and butoxy groups can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing advanced organic electronic materials, including charge-transport layers and emissive compounds for displays and lighting.
• Polymer & Resin Modifier: Incorporated as a functional monomer or cross-linking agent to create specialty polymers with tailored thermal, optical, or chemical resistance properties.
• Dye & Pigment Intermediate: Utilized in the production of complex organic dyes and pigments, where its structure contributes to color fastness and specific hue characteristics.
• Research & Development: A versatile reagent for academic and industrial research in organic chemistry, medicinal chemistry, and materials science.

Basic Information

Product Name	2-Butoxy-3,4-Difluorobenzenamine
CAS No.	935251-05-1
Molecular Formula	C₁₀H₁₃F₂NO
Molecular Weight	201.21 g/mol
Synonyms	3,4-Difluoro-2-butoxyaniline; 2-Amino-4,5-difluorophenyl butyl ether; 2-Butoxy-3,4-difluoroaniline; 4,5-Difluoro-2-butoxybenzenamine; Benzenamine, 2-butoxy-3,4-difluoro-; 935251-05-1 (CAS Registry)
EINECS	Contact for details

Quality Control

Every batch of 2-Butoxy-3,4-Difluorobenzenamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and tendency for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to amber liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.