Description

Hdac-In-4 CAS NO 934828-12-3 is a potent and selective small molecule inhibitor of histone deacetylase (HDAC) enzymes, a key target class in epigenetic research and therapeutic development. This compound matters for its role in modulating gene expression and chromatin structure, enabling critical studies in oncology, neurology, and other disease areas. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel epigenetic therapies and understanding disease mechanisms.

Application

• Epigenetic Research Tool: Used as a selective chemical probe to study the biological function and inhibition of specific HDAC isoforms in cellular and biochemical assays.
• Oncology Research: Investigated for its potential to induce cell cycle arrest, differentiation, and apoptosis in various cancer cell lines, supporting anti-cancer drug discovery.
• Neurological Disease Models: Applied in research models for neurodegenerative and psychiatric disorders where HDAC modulation is a promising therapeutic strategy.
• Inflammatory & Autoimmune Disease Studies: Utilized to explore the role of HDACs in regulating immune cell function and cytokine production.
• Chemical Biology: Serves as a key scaffold for structure-activity relationship (SAR) studies and the design of next-generation HDAC inhibitors.
• Preclinical Development: Supports pharmacokinetic, pharmacodynamic, and toxicology studies in the early stages of therapeutic candidate development.

Basic Information

Product Name	Hdac-In-4
CAS No.	934828-12-3
Molecular Formula	C₂₁H₂₀N₄O₃
Molecular Weight	376.41 g/mol
Synonyms	HDAC-IN-4; HDAC Inhibitor IV; N-Hydroxy-4-[[(2S)-2-[[4-(Dimethylamino)phenyl]amino]-1-oxo-3-phenylpropyl]amino]benzamide; (2S)-N-Hydroxy-2-[[4-(dimethylamino)phenyl]amino]-4-phenyl-N-[4-(hydroxycarbamoyl)phenyl]butanamide; HDACi 4; Histone Deacetylase Inhibitor 4
EINECS	Contact for details

Quality Control

Our Hdac-In-4 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.