Description

Casein Kinase II Inhibitor III is a potent and selective small molecule inhibitor of the CK2 protein kinase, a key regulator of numerous cellular processes. This compound is essential for researchers investigating signaling pathways related to cell growth, proliferation, and apoptosis. It is primarily utilized in biochemical and pharmacological research, including target validation, high-throughput screening, and the study of cancer, neurological disorders, and viral infections.

Application

• Biochemical Research: Used as a selective tool compound to study CK2-mediated phosphorylation events and signaling cascades in vitro.
• Cancer Research: Investigated for its potential to inhibit tumor cell growth and proliferation by targeting CK2 activity in various cancer models.
• Drug Discovery: Serves as a reference standard and lead compound in high-throughput screening campaigns for developing novel kinase inhibitors.
• Neuroscience Studies: Applied in research exploring the role of CK2 in neurological functions and disorders, including Alzheimer's disease.
• Virology Research: Used to study the dependency of certain viruses on host CK2 activity for replication.
• Cellular Pathway Analysis: A critical reagent for dissecting the role of CK2 in cell cycle regulation, DNA repair, and apoptosis.

Basic Information

Product Name	Casein Kinase II Inhibitor III
CAS No.	934358-00-6
Molecular Formula	C₂₀H₁₅N₅O₂
Molecular Weight	357.37 g/mol
Synonyms	CK2 Inhibitor III; 2,8-Dihydroxy-4-methyl-9-phenyl-1,8a-dihydroimidazo[1,2-a]purin-6(9H)-one; 4-Methyl-2,8-dihydroxy-9-phenyl-1,8a-dihydroimidazo[1,2-a]purin-6(9H)-one; TBBz; 4,5,6,7-Tetrabromobenzotriazole derivative; Casein Kinase 2 Inhibitor III
EINECS	Contact for details

Quality Control

Our Casein Kinase II Inhibitor III is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals to guarantee reliable and reproducible experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.