Description

1,2-Oxazole-4-Sulfonyl Chloride is a versatile and reactive chemical intermediate, primarily valued for its role as a key sulfonylation reagent in organic synthesis. Its significance lies in enabling the efficient introduction of the 1,2-oxazole-4-sulfonyl moiety, a valuable functional group in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the sulfonyl chloride group facilitates the creation of potent bioactive molecules.
• Functional Material Development: Serves as a precursor for creating specialized polymers, ligands, or surface-modifying agents with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in research applications.
• Cross-Coupling & Catalysis: Acts as a substrate or reagent in metal-catalyzed cross-coupling reactions to construct complex heterocyclic architectures.
• Dye & Pigment Chemistry: Utilized in the synthesis of specialized dyes and pigments containing sulfonated heterocyclic structures.

Basic Information

Product Name	1,2-Oxazole-4-Sulfonyl Chloride
CAS No.	933740-94-4
Molecular Formula	C3H2ClNO3S
Molecular Weight	167.57 g/mol
Synonyms	4-Isoxazolesulfonyl chloride; Isoxazole-4-sulfonyl chloride; 1,2-Oxazole-4-sulfonyl chloride; 4-Sulfonylchloride isoxazole; Oxazole-4-sulfonyl chloride; 933740-94-4; 4-Isoxazolesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 1,2-Oxazole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.