Description

1,2,5-Trifluoro-4-Methyl-3-Trifluoromethyl-Benzene is a high-value, multi-fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group and a specific pattern of fluorine substituents, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine pattern enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the synthesis of electronic chemicals for display and lighting technologies, improving dielectric anisotropy and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, fluorinated aromatic systems for various R&D purposes.

Basic Information

Product Name	1,2,5-Trifluoro-4-Methyl-3-Trifluoromethyl-Benzene
CAS No.	933674-92-1
Molecular Formula	C9H5F6
Molecular Weight	236.13 g/mol
Synonyms	3-(Trifluoromethyl)-1,2,5-trifluoro-4-methylbenzene; 4-Methyl-1,2,5-trifluoro-3-(trifluoromethyl)benzene; 1,2,5-Trifluoro-4-methyl-3-(trifluoromethyl)benzene; Benzene, 1,2,5-trifluoro-4-methyl-3-(trifluoromethyl)-; 3-Trifluoromethyl-1,2,5-trifluoro-4-methylbenzene
EINECS	Contact for details

Quality Control

Our 1,2,5-Trifluoro-4-Methyl-3-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.