Description

2-Methoxy-4-Methyl-5-Nitrobenzotrifluoride is a specialized fluorinated aromatic nitro compound that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and nitro-substituted methoxybenzene structure makes it a valuable intermediate for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a trifluoromethylphenyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups enhance biological activity and stability.
• Material Science Research: Employed in the creation of advanced organic materials, including liquid crystals and specialty polymers.
• Dye and Pigment Intermediate: Serves as a building block for synthesizing complex dyes and pigments with specific color and fastness properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	2-Methoxy-4-Methyl-5-Nitrobenzotrifluoride
CAS No.	933673-45-1
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	1-Methoxy-2-methyl-5-nitro-4-(trifluoromethyl)benzene; 4-Methyl-2-methoxy-5-nitrobenzotrifluoride; 5-Nitro-2-methoxy-4-methylbenzotrifluoride; 2-Methoxy-4-methyl-5-nitro-α,α,α-trifluorotoluene; 4-(Trifluoromethyl)-2-methoxy-5-nitrotoluene; 2-Methyl-5-nitro-4-(trifluoromethyl)anisole
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Methyl-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.