Description

1-(Dimethoxymethyl)-2-Fluoro-4-Iodobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents on a benzene ring activated by a dimethoxymethyl group, makes it a versatile intermediate for constructing complex molecules. This compound is particularly valuable for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key functional groups and create novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogenated aromatic cores for bioactivity or as coupling partners.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and iodine atoms can enhance metabolic stability and binding affinity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic structure.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form biaryl and other complex structures.
• Fluorine Chemistry: The presence of a fluorine atom allows for further derivatization and study of fluorine's effects on molecular properties in medicinal chemistry.
• Chemical Reference Standard: Used as a pure standard in analytical laboratories for method development and quality control of related compounds.

Basic Information

Product Name	1-(Dimethoxymethyl)-2-Fluoro-4-Iodobenzene
CAS No.	933672-22-1
Molecular Formula	C9H10FIO2
Molecular Weight	296.08 g/mol
Synonyms	2-Fluoro-4-iodobenzaldehyde dimethyl acetal; (2-Fluoro-4-iodophenyl)(dimethoxy)methane; Benzene, 1-(dimethoxymethyl)-2-fluoro-4-iodo-; α,α-Dimethoxy-2-fluoro-4-iodotoluene
EINECS	Contact for details

Quality Control

Our 1-(Dimethoxymethyl)-2-Fluoro-4-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.