Description

Cddo-Ea is a synthetic oleanane triterpenoid derivative with significant research and development interest. This compound matters for its potent biological activity as an inducer of the Nrf2 pathway, which plays a crucial role in cellular defense against oxidative stress and inflammation. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutics for conditions involving chronic inflammation, cancer, and neurodegenerative diseases.

Application

• Pharmaceutical Research & Development: A key intermediate or active pharmaceutical ingredient (API) in the development of novel anti-inflammatory and cytoprotective drugs.
• Preclinical Studies: Used in in vitro and in vivo models to investigate the Nrf2-Keap1 signaling pathway and its therapeutic potential.
• Chemical Biology Probes: Serves as a tool compound for studying mechanisms of oxidative stress response and identifying new molecular targets.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biomarker Research: Utilized in studies exploring the modulation of antioxidant and detoxification enzymes.

Basic Information

Item	Detail
Product Name	Cddo-Ea
CAS No.	932730-51-3
Molecular Formula	C32H44O4
Molecular Weight	492.70 g/mol
Synonyms	2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Ethyl Ester; Ethyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; CDDO-EA; RTA 405; TP-225; Bardoxolone Ethyl Ester; Triterpenoid CDDO Ethyl Ester
EINECS	Contact for details

Quality Control

Our Cddo-Ea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity and identity confirmation by NMR and MS. A detailed Certificate of Analysis (COA) documenting all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C to prevent oxidation and degradation. The container should be kept in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.