Description

4-Iodo-2-Methyl-1-(Trifluoromethyl)Benzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring iodine, methyl, and trifluoromethyl substituents, provides a versatile scaffold for introducing complexity and specific electronic properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Building Block: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Cross-Coupling Reactions: Serves as a superior substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for constructing complex biaryl systems.
• Fluorine Chemistry Research: An important reagent for studying the effects of fluorine substitution on molecular properties in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and reference standards.

Basic Information

Product Name	4-Iodo-2-Methyl-1-(Trifluoromethyl)Benzene
CAS No.	930599-57-8
Molecular Formula	C8H6F3I
Molecular Weight	286.04 g/mol
Synonyms	2-Methyl-4-iodobenzotrifluoride; 1-Iodo-3-methyl-4-(trifluoromethyl)benzene; 4-Iodo-α,α,α-trifluoro-o-xylene; 2-Methyl-α,α,α-trifluoro-4-iodotoluene; 4-Iodo-2-methylbenzotrifluoride; 4-Iodo-2-methyl-1-(trifluoromethyl)benzene; 2-Methyl-4-iodo-1-(trifluoromethyl)benzene; 4-Iodo-2-methyl-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 4-Iodo-2-Methyl-1-(Trifluoromethyl)Benzene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets a typical purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and relevant physical data. We support custom synthesis projects requiring specific purity grades (e.g., ≥98%, ≥99%) for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.