Description

1-Bromo-2-Fluoro-4-Isopropylbenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective further functionalization in complex molecule construction. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isopropyl and halogen groups for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine atom.
• Fluorine Chemistry Research: The presence of both fluorine and bromine makes it a valuable probe in studying structure-activity relationships (SAR) and metabolic stability.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Bromo-2-Fluoro-4-Isopropylbenzene
CAS No.	930599-54-5
Molecular Formula	C9H10BrF
Molecular Weight	217.08 g/mol
Synonyms	2-Bromo-1-Fluoro-4-Isopropylbenzene; 4-Isopropyl-1-bromo-2-fluorobenzene; 1-Bromo-2-fluoro-4-(1-methylethyl)benzene; 2-Fluoro-4-isopropylbromobenzene; (4-Isopropyl-2-fluorophenyl)bromide; 930599-54-5; Benzene, 1-bromo-2-fluoro-4-(1-methylethyl)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-4-Isopropylbenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.