Description

1,3-Dichloroisoquinoline-5-Sulfonyl Chloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its significance lies in its dual reactive sites, which enable its use as a key intermediate for constructing complex heterocyclic and sulfonamide-based compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for functional polymers, dyes, and photoactive materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Sulfonamide Library Production: Enables the efficient parallel synthesis of diverse sulfonamide compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	1,3-Dichloroisoquinoline-5-Sulfonyl Chloride
CAS No.	930396-16-0
Molecular Formula	C9H4Cl3NO2S
Molecular Weight	296.56 g/mol
Synonyms	5-(Chlorosulfonyl)-1,3-dichloroisoquinoline; 1,3-Dichloro-5-chlorosulfonylisoquinoline; 1,3-Dichloroisoquinoline-5-sulfonyl chloride; Isoquinoline-5-sulfonyl chloride, 1,3-dichloro-; 930396-16-0
EINECS	Contact for details

Quality Control

Our 1,3-Dichloroisoquinoline-5-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.