Description

Boronic Acid, B-(2-Fluoro-5-Methyl-4-Pyridinyl)- is a high-value organoboron building block, specifically a pyridinyl-substituted boronic acid derivative. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical industry for constructing complex molecules and developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require the specific 2-fluoro-5-methylpyridine moiety.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological systems.
• Process Chemistry & Scale-up: Essential for route scouting and optimization in kilo-lab and pilot plant production of target molecules.
• Custom Synthesis & Contract Manufacturing: A requested starting material for custom synthesis projects in fine chemical manufacturing.

Basic Information

Product Name	Boronic Acid, B-(2-Fluoro-5-Methyl-4-Pyridinyl)-
CAS No.	929194-41-2
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(2-Fluoro-5-methylpyridin-4-yl)boronic acid; 4-Pyridineboronic acid, 2-fluoro-5-methyl-; B-(2-Fluoro-5-methyl-4-pyridinyl)boronic acid; 2-Fluoro-5-methyl-4-pyridinylboronic acid; 2-Fluoro-5-methylpyridine-4-boronic acid; 4-Borono-2-fluoro-5-methylpyridine
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-(2-Fluoro-5-Methyl-4-Pyridinyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.