Description

Seladelpar Lysine is a lysine salt form of the selective peroxisome proliferator-activated receptor delta (PPARδ) agonist, Seladelpar. This compound is of significant interest in pharmaceutical research and development due to its potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of treatments for metabolic and liver diseases.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) or advanced intermediate in the synthesis of investigational drug formulations.
• Metabolic Disease Research: Used in preclinical and clinical research targeting metabolic disorders, including non-alcoholic steatohepatitis (NASH) and primary biliary cholangitis (PBC).
• PPARδ Agonist Studies: Employed as a reference standard or experimental compound in biochemical and pharmacological studies focusing on PPARδ receptor activation pathways.
• Formulation Development: Utilized in the development of various dosage forms, leveraging the lysine salt for improved solubility and stability profiles.
• Analytical Reference Standard: Acts as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in regulatory and R&D settings.

Basic Information

Product Name	Seladelpar Lysine
CAS No.	928821-40-3
Molecular Formula	C24H28FN3O4 • C6H14N2O2
Molecular Weight	584.66 g/mol
Synonyms	MBX-8025 Lysine Salt; Seladelpar L-Lysinate; GW-501516 Lysine Salt; 2-Methyl-4-((4-methyl-2-(4-(trifluoromethyl)phenyl)-1,3-thiazol-5-yl)methylthio)phenoxyacetic Acid Lysine Salt; (2-Methyl-4-(((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)thio)phenoxy)acetic Acid Compound with L-Lysine; PPARδ Agonist Lysine Salt.
EINECS	Contact for details

Quality Control

Our Seladelpar Lysine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.