Description

Phocaecholic Acid is a high-purity bile acid derivative, a critical intermediate in the synthesis of pharmaceutical compounds. Its value lies in its specific stereochemistry and purity, which are essential for producing active pharmaceutical ingredients (APIs) with precise biological activity. This product is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents, particularly in hepatology and metabolic disease research.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, liver function, and membrane biology.
• API Synthesis: Serves as a crucial precursor in the multi-step production of complex active pharmaceutical ingredients.
• Metabolite Standard: Employed in analytical laboratories for method development and calibration in LC-MS and HPLC analyses.
• Cell Culture & In Vitro Studies: Utilized in biological assays to study cellular signaling pathways and receptor interactions.

Basic Information

Product Name	Phocaecholic Acid
CAS No.	105369-89-9
Molecular Formula	C26H44O5
Molecular Weight	436.63 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid; 3α,7α,12α-Trihydroxy-5β-cholanoic Acid; Phoca Cholic Acid; (3α,5β,7α,12α)-3,7,12-Trihydroxycholan-24-oic Acid; 5β-Cholan-24-oic acid-3α,7α,12α-triol; 3α,7α,12α-Trihydroxy-5β-cholanic Acid
EINECS	Contact for details

Quality Control

Our Phocaecholic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.