Description

Tiopronin CAS NO 1953-02-2 is a synthetic thiol compound, chemically known as N-(2-mercaptopropionyl)glycine. This active pharmaceutical ingredient (API) is valued for its potent antioxidant and chelating properties, making it a critical component in advanced therapeutic formulations. It is primarily sought by pharmaceutical manufacturers and research institutions for the development and production of treatments for conditions such as cystinuria and liver disorders, where its ability to reduce disulfide bonds is essential.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for cystinuria, a genetic disorder leading to kidney stone formation.
• Hepatoprotective Agent: Incorporated into formulations for treating liver diseases, including hepatitis and drug-induced liver injury, due to its detoxifying effects.
• Antioxidant in Research: Utilized in biochemical and pharmacological research to study oxidative stress mechanisms and evaluate protective compounds.
• Chelating Therapy: Investigated for its potential in heavy metal detoxification protocols, leveraging its thiol group's affinity for metal ions.
• Intermediate for Synthesis: Serves as a key building block in the synthesis of more complex thiol-based pharmaceutical compounds.

Basic Information

Product Name	Tiopronin
CAS No.	1953-02-2
Molecular Formula	C5H9NO3S
Molecular Weight	163.19 g/mol
Synonyms	N-(2-Mercaptopropionyl)glycine; Thiola; Acadione; α-Mercaptopropionylglycine; MPG; Tiopronina; Tioproninum; (2-Mercaptopropanoylamino)acetic acid
EINECS	217-791-8

Quality Control

Our Tiopronin is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch is tested against rigorous specifications for identity, purity, and potency, aligning with pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.