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Tauroursodeoxycholic Acid CAS NO 14605-22-2


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CAS No.:14605-22-2

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

Tauroursodeoxycholic Acid is a water-soluble, conjugated bile acid derivative known for its cytoprotective and anti-apoptotic properties. This high-purity compound is critical for pharmaceutical research and development, particularly in hepatology and neurology. It serves as a key active pharmaceutical ingredient (API) and reference standard for manufacturers and research institutions worldwide.

Application

  • Pharmaceutical API: Primary ingredient in formulations for treating cholestatic liver diseases, such as primary biliary cholangitis (PBC).
  • Neuroprotective Research: Investigated in preclinical and clinical studies for neurodegenerative conditions, including Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's disease.
  • Cell Culture & Biochemistry: Used as a chemical chaperone to reduce endoplasmic reticulum (ER) stress and improve protein folding in vitro.
  • Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and method development in pharmaceutical testing labs.
  • Metabolic Disorder Studies: Employed in research exploring bile acid metabolism and its role in metabolic syndromes.
  • Ophthalmology: Studied for potential therapeutic effects in retinal degenerative diseases.

Basic Information

Product Name Tauroursodeoxycholic Acid
CAS No. 14605-22-2
Molecular Formula C₂₆H₄₅NO₆S
Molecular Weight 499.71 g/mol
Synonyms Tauroursodeoxycholate; TUDCA; Ursotaurine; Tauro-ursodeoxycholic Acid; 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid; UR 906; Taurousodiol
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Quality Control

Our Tauroursodeoxycholic Acid is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤2.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Related Substances (HPLC) Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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