Description

Ademetionine is a critical biochemical compound, serving as the principal biological methyl donor in numerous enzymatic transmethylation reactions. Its role is fundamental in supporting liver function, cellular regeneration, and the synthesis of neurotransmitters. This high-purity material is essential for manufacturers in the pharmaceutical and nutraceutical industries, particularly for producing hepatoprotective agents, mood disorder therapeutics, and premium dietary supplements. Ademetionine CAS NO 1253909-57-7 is supplied to meet the stringent demands of advanced research and commercial production.

Application

• Pharmaceutical Active Ingredient (API): Core component in formulations for treating liver disorders such as intrahepatic cholestasis, cirrhosis, and drug-induced hepatotoxicity.
• Nutraceutical & Dietary Supplements: Used in premium supplements aimed at supporting liver health, joint function, and mood regulation.
• Biochemical Research: Essential reagent in studies of methylation pathways, epigenetics, and cellular metabolism.
• Veterinary Medicine: Incorporated into treatments for hepatic conditions in companion and production animals.
• Cosmeceutical Preparations: Utilized in advanced skincare products for its role in antioxidant synthesis and cellular repair.

Basic Information

Product Name	Ademetionine
CAS No.	1253909-57-7
Molecular Formula	C15H23N6O5S+
Molecular Weight	399.45 g/mol
Synonyms	S-Adenosylmethionine; SAM; SAMe; AdoMet; S-Adenosyl-L-methionine; (3S)-5'-[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine; Adenosine-5'-(3-amino-3-carboxypropyl)methylsulfonium salt
EINECS	Contact for details

Quality Control

Our Ademetionine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and stringent limits for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized. For short-term use, allow the sealed container to equilibrate to room temperature before opening to prevent condensation. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-48° to -52° (c=1 in 0.1N HCl)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.