Description

Ademetionine 1,4-Butanedisulfonate is a high-purity, stable salt form of S-adenosylmethionine (SAMe), a critical biochemical cofactor. This compound is essential for research and development in pharmaceutical applications, particularly for its role in methylation, transsulfuration, and aminopropylation pathways. It is primarily utilized by pharmaceutical manufacturers, nutraceutical formulators, and advanced biochemical research institutions seeking a reliable and well-characterized source of this vital metabolite.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of prescription drugs targeting liver disorders, depression, and osteoarthritis.
• Nutraceutical & Dietary Supplement Formulation: Used in the production of high-grade SAMe supplements, where the 1,4-butanedisulfonate salt offers enhanced stability and bioavailability.
• Biochemical Research & Development: A crucial reagent for studying cellular methylation processes, gene expression, and the biochemistry of liver function and neurological health.
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Cell Culture & Microbiology: Used in specialized media to support the growth and study of microorganisms or cell lines requiring exogenous SAMe.

Basic Information

Product Name	Ademetionine 1,4-Butanedisulfonate
CAS No.	1014692-62-6
Molecular Formula	C15H23N6O5S • C4H8O6S2
Molecular Weight	662.73 g/mol
Synonyms	S-Adenosylmethionine 1,4-Butanedisulfonate; SAMe 1,4-Butanedisulfonate; AdoMet 1,4-Butanedisulfonate; SAM-e Butanedisulfonate; S-Adenosyl-L-methionine Butanedisulfonate; (3S)-5'-[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine 1,4-Butanedisulfonate; Ademetionine Butanedisulfonate
EINECS	Contact for details

Quality Control

Our Ademetionine 1,4-Butanedisulfonate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications suitable for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.