Description

Tauroursodeoxycholate Dihydrate is a high-purity, conjugated bile acid derivative, specifically the taurine conjugate of ursodeoxycholic acid. This compound is of significant value in pharmaceutical research and development due to its role as a potent endoplasmic reticulum (ER) stress inhibitor and cytoprotective agent. It is primarily sought after by researchers and manufacturers in the life sciences sector for applications in cell culture, drug discovery, and the formulation of reference standards.

Application

• Pharmaceutical Research & Drug Development: Used as a key active pharmaceutical ingredient (API) intermediate or reference standard in metabolic and liver disease research.
• Cell Biology & Biochemistry: Employed as a chemical chaperone to reduce ER stress in in vitro cell culture studies and experimental models.
• Academic & Clinical Research: Serves as a critical reagent for investigating apoptosis, neurodegenerative diseases, and diabetes.
• Biopharmaceutical Production: Can be utilized in media supplements or process optimization to improve cell viability in bioreactors.
• Analytical Chemistry: Acts as a certified reference material (CRM) for method development and quality control in analytical laboratories.

Basic Information

Product Name	Tauroursodeoxycholate Dihydrate
CAS No.	117609-50-4
Molecular Formula	C26H45NO6S · 2H2O
Molecular Weight	535.70 g/mol (Dihydrate)
Synonyms	Tauroursodeoxycholic Acid Dihydrate; TUDCA Dihydrate; Ursodoxicoltaurine Dihydrate; 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid Dihydrate; Tauro-ursodeoxycholic Acid Dihydrate; UR-906; Taurousodiol Dihydrate
EINECS	Contact for details

Quality Control

Our Tauroursodeoxycholate Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	5.0% - 7.0%
Specific Rotation	+28.0° to +32.0° (c=1, in Ethanol)
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.