Description

Ademethionine 1,4-Butanedisulfonate is a stable, water-soluble salt form of S-adenosylmethionine (SAMe), a critical biochemical cofactor. This compound is essential for its role in supporting key metabolic pathways, including methylation, transsulfuration, and aminopropylation. It is primarily utilized in the pharmaceutical and nutraceutical industries for the formulation of high-quality dietary supplements and active pharmaceutical ingredients (APIs) targeting liver health, joint function, and mood support.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of advanced pharmaceutical products.
• Nutraceutical Formulations: Incorporated into high-purity dietary supplements for liver support, joint health, and cognitive well-being.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and cell culture applications.
• Veterinary Medicine: Applied in formulations for animal health, particularly for hepatic support and metabolic function.
• Cosmeceuticals: Explored for use in topical formulations aimed at skin health and anti-aging due to its role in cellular processes.

Basic Information

Product Name	Ademethionine 1,4-Butanedisulfonate
CAS No.	101020-79-5
Molecular Formula	C19H29N6O11S3
Molecular Weight	629.68 g/mol
Synonyms	S-Adenosylmethionine 1,4-Butanedisulfonate; SAMe 1,4-Butanedisulfonate; Ademetionine 1,4-Butanedisulfonate; AdoMet Butanedisulfonate; SAM Butanedisulfonate; S-Adenosyl-L-methionine Butanedisulfonate; (3S)-5'-[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine 1,4-Butanedisulfonate
EINECS	Contact for details

Quality Control

Our Ademethionine 1,4-Butanedisulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) documenting purity, heavy metals, residual solvents, and microbiological data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Microbiological Analysis	Meets standard limits for total aerobic count, yeast, and mold

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.