Description

2-Fluoro-5-Iodobenzotrifluoride is a high-value, multi-functional halogenated aromatic building block, essential for advanced chemical synthesis. Its unique structure, featuring fluorine, iodine, and a trifluoromethyl group, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and iodine substituents can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing fluorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to create complex biaryl and conjugated systems.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in organic molecules.
• Functional Material Development: Employed in the synthesis of specialty polymers, ligands for catalysis, and advanced organic frameworks with tailored properties.

Basic Information

Product Name	2-Fluoro-5-Iodobenzotrifluoride
CAS No.	928783-87-3
Molecular Formula	C7H3F4I
Molecular Weight	305.99 g/mol
Synonyms	1-Fluoro-4-iodo-2-(trifluoromethyl)benzene; 2-Fluoro-α,α,α-trifluoro-5-iodotoluene; 5-Iodo-2-fluorobenzotrifluoride; 2-Fluoro-5-iodobenzotrifluoride; 2-Fluoro-5-iodo-α,α,α-trifluorotoluene; 1-Iodo-4-fluoro-3-(trifluoromethyl)benzene; Benzene, 1-fluoro-4-iodo-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.