Description

4-Bromo-2,3-Difluorotoluene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, where the bromine and fluorine substituents enable selective cross-coupling and functionalization reactions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorotoluene moiety contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to construct biaryl systems.
• Fluorine Chemistry Research: An important reagent for studying the effects of fluorine substitution on aromatic systems in medicinal and materials chemistry.
• Specialty Polymer Monomer: Can be utilized to introduce fluorine and bromine functional groups into polymer backbones for specialized material properties.

Basic Information

Product Name	4-Bromo-2,3-Difluorotoluene
CAS No.	928304-47-6
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	1-Bromo-4-methyl-2,3-difluorobenzene; 2,3-Difluoro-4-bromotoluene; 4-Bromo-2,3-difluoro-1-methylbenzene; Toluene, 4-bromo-2,3-difluoro-; 928304-47-6; 4-Bromo-2,3-difluoromethylbenzene
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,3-Difluorotoluene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.