Description

1-Bromo-4-Ethyl-2-Fluorobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and an ethyl substituent, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated and brominated aromatic motifs which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogenated benzene core is a common structural element.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated organic semiconductors, liquid crystal compounds, and electron-transport materials in display technologies.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom, enabling the formation of new carbon-carbon bonds.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating specialized ligand systems for catalysis.
• Fluorine Chemistry Studies: Used as a model compound in studying the effects of fluorine substitution on aromatic reactivity and physical properties.

Basic Information

Product Name	1-Bromo-4-Ethyl-2-Fluorobenzene
CAS No.	928304-44-3
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	4-Ethyl-2-fluorobromobenzene; 2-Fluoro-4-ethylbromobenzene; 1-Bromo-4-ethyl-2-fluorobenzene; 2-Fluoro-4-ethyl-1-bromobenzene; 4-Ethyl-2-fluoro-1-bromobenzene; (4-Ethyl-2-fluorophenyl)bromide; 928304-44-3
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-4-Ethyl-2-Fluorobenzene is manufactured and tested under a strict quality management system. We ensure high lot-to-lot consistency through rigorous analytical controls, including GC, HPLC, and NMR, to meet the precise requirements of synthesis and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.