Description

2-Isopropyl-Cyclopropanesulfonyl Chloride is a specialized organosulfur compound featuring a reactive sulfonyl chloride group on a cyclopropane scaffold. This high-purity intermediate is critical for introducing the unique steric and electronic properties of the cyclopropane ring into target molecules during advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the cyclopropane moiety can enhance biological activity.
• Chemical Biology Probe Development: Employed to create activity-based probes (ABPs) and other research tools for studying enzyme function and mechanism.
• Material Science Research: Serves as a precursor for functionalized polymers or small molecules with tailored properties for electronic or coating applications.
• Sulfonamide Library Synthesis: The reactive sulfonyl chloride group enables efficient parallel synthesis of diverse sulfonamide libraries for high-throughput screening.

Basic Information

Product Name	2-Isopropyl-Cyclopropanesulfonyl Chloride
CAS No.	927636-25-7
Molecular Formula	C6H11ClO2S
Molecular Weight	182.67 g/mol
Synonyms	Cyclopropanesulfonyl chloride, 2-(1-methylethyl)-; 2-Isopropylcyclopropane-1-sulfonyl chloride; 1-Cyclopropanesulfonyl chloride, 2-isopropyl-; 2-(Propan-2-yl)cyclopropane-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Isopropyl-Cyclopropanesulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.