Description

3-[(6-Methylpyrazin-2-Yl)Oxy]Benzenesulphonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its primary value lies in its reactive sulfonyl chloride group, which enables efficient sulfonamide bond formation, a key step in creating complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its unique pyrazine-oxygen linkage for enhanced bioactivity.
• Chemical Biology Probe Development: Serves as a versatile handle for labeling proteins or creating activity-based probes (ABPs) due to its electrophilic sulfonyl chloride moiety.
• Material Science Research: Employed in the synthesis of specialized polymers and functional materials requiring sulfonamide linkages for specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	3-[(6-Methylpyrazin-2-Yl)Oxy]Benzenesulphonyl Chloride
CAS No.	926921-65-5
Molecular Formula	C11H9ClN2O3S
Molecular Weight	284.72 g/mol
Synonyms	3-[(6-Methyl-2-pyrazinyl)oxy]benzenesulfonyl chloride; 3-((6-Methylpyrazin-2-yl)oxy)benzenesulfonyl chloride; 3-(6-Methylpyrazin-2-yloxy)benzenesulfonyl chloride; 1-Chlorosulfonyl-3-[(6-methylpyrazin-2-yl)oxy]benzene; Benzenesulfonyl chloride, 3-[(6-methyl-2-pyrazinyl)oxy]-; 926921-65-5
EINECS	Contact for details

Quality Control

Our 3-[(6-Methylpyrazin-2-Yl)Oxy]Benzenesulphonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and ensures reliable performance in your critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.