Description

6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a versatile electrophilic reagent for introducing the sulfonamide moiety, enabling the creation of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting enzyme inhibition or requiring specific sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the sulfonyl group enhances biological activity and selectivity.
• Dye and Pigment Manufacturing: Serves as a reactive intermediate for creating specialized sulfonamide-based dyes and colorants with improved fastness and solubility.
• Polymer Chemistry: Employed in the modification of polymers to introduce sulfonamide functional groups, altering material properties like hydrophilicity or ionic conductivity.
• Chemical Research & Development: A valuable tool for medicinal and synthetic chemists exploring new chemical entities and reaction pathways in academic and industrial R&D settings.
• Ligand and Catalyst Design: Useful for constructing complex ligands and organocatalysts used in asymmetric synthesis and metal coordination chemistry.

Basic Information

Product Name	6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Sulfonyl Chloride
CAS No.	926246-59-5
Molecular Formula	C6H8ClN3O4S
Molecular Weight	253.66 g/mol
Synonyms	5-Sulfonyl Chloride-6-Amino-1,3-Dimethyluracil; 6-Amino-1,3-Dimethyl-5-sulfonylchloridouracil; 6-Amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione-5-sulfonyl chloride; 1,3-Dimethyl-6-amino-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride; ADTU-SO2Cl; 6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride; 6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.