Description

4-Fluoro-3-(1H-Tetrazol-5-Yl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group and tetrazole heterocycle. This compound matters for its critical role in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of key pharmacophores. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, particularly in areas like enzyme inhibition and receptor antagonism.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging the bioactivity of the tetrazole moiety.
• Material Science Research: Serves as a precursor for creating functional polymers or metal-organic frameworks (MOFs) with specific sulfonyl-linked properties.
• Chemical Biology Probes: Employed in the design of activity-based probes and labeling reagents for proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, small-scale to pilot-scale production runs.

Basic Information

Item	Details
Product Name	4-Fluoro-3-(1H-Tetrazol-5-Yl)Benzenesulfonyl Chloride
CAS No.	926222-53-9
Molecular Formula	C7H4ClFN4O2S
Molecular Weight	262.64 g/mol
Synonyms	4-Fluoro-3-(1H-tetrazol-5-yl)benzenesulfonyl chloride; 3-(1H-Tetrazol-5-yl)-4-fluorobenzenesulfonyl chloride; 4-Fluoro-3-(2H-tetrazol-5-yl)benzenesulfonyl chloride; 926222-53-9; 4-Fluoro-3-(tetrazol-5-yl)benzenesulfonyl chloride; 5-(5-Chlorosulfonyl-2-fluorophenyl)-1H-tetrazole; 2-Fluoro-5-(1H-tetrazol-5-yl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(1H-Tetrazol-5-Yl)Benzenesulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, and we support compliance with relevant cGMP and ISO 9001 quality management standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.