Description

5-(1H-Tetrazol-5-Yl)Pyrrol-2-Sulfonyl Chloride is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular architecture, featuring both a tetrazole ring and a reactive sulfonyl chloride group, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting cardiovascular, metabolic, and central nervous system disorders, where the tetrazole moiety acts as a bioisostere for carboxylic acids.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure to enhance biological activity and environmental profile.
• Material Science Research: Serves as a building block for creating specialty polymers, ligands for catalysis, and advanced organic frameworks (MOFs/COFs) with tailored properties.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes and affinity tags due to the reactivity of the sulfonyl chloride group for selective conjugation with biomolecules.
• Academic & Contract Research: A vital reagent for methodological development in organic chemistry and for exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	5-(1H-Tetrazol-5-Yl)Pyrrol-2-Sulfonyl Chloride
CAS No.	924964-22-7
Molecular Formula	C5H4N6O2SCl
Molecular Weight	232.64 g/mol
Synonyms	5-(1H-Tetrazol-5-yl)-1H-pyrrole-2-sulfonyl chloride; 1H-Pyrrole-2-sulfonyl chloride, 5-(1H-tetrazol-5-yl)-; 5-(1H-Tetrazol-5-yl)pyrrole-2-sulfonyl chloride; Tetrazolylpyrrole sulfonyl chloride; Pyrroletetrazole sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(1H-Tetrazol-5-Yl)Pyrrol-2-Sulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.