Description

Adiporon is a potent and selective small molecule agonist of the adiponectin receptor (AdipoR1/AdipoR2), playing a crucial role in metabolic regulation and insulin sensitization pathways. This compound is of significant interest for research into metabolic disorders, including type 2 diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD). It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology and metabolic disease therapeutics.

Application

• Pharmaceutical Research & Development: A key tool compound for investigating adiponectin signaling pathways and validating AdipoR1/AdipoR2 as therapeutic targets.
• Metabolic Disease Studies: Used in preclinical in vitro and in vivo models to study insulin resistance, glucose homeostasis, and lipid metabolism.
• Anti-inflammatory Research: Employed to explore the anti-inflammatory effects mediated through adiponectin receptor activation in various disease contexts.
• Cardiovascular Research: Investigated for its potential protective roles in atherosclerosis and other cardiovascular conditions linked to metabolic syndrome.
• Academic & Institutional Research: Serves as a critical reagent for basic science research in biochemistry, molecular biology, and physiology departments.
• Biomarker Discovery: Used in assays to identify downstream biomarkers of adiponectin receptor activation.

Basic Information

Product Name	Adiporon
CAS No.	924416-43-3
Molecular Formula	C₁₉H₂₀N₄O₂
Molecular Weight	336.39 g/mol
Synonyms	AdipoRon; 2-((2-(1H-Indol-3-yl)ethyl)amino)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1(2H)-one; Adiponectin Receptor Agonist; AdipoR Agonist; AdipoRon (Adiporon); BML-275 derivative; AdipoR1/R2 agonist
EINECS	Contact for details

Quality Control

Our Adiporon is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each batch is accompanied by comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.