Description

Elafibranor (GFT505) is a potent, dual peroxisome proliferator-activated receptor (PPAR) α/δ agonist with significant therapeutic potential. This high-purity active pharmaceutical ingredient (API) is critical for research and development in metabolic and liver diseases. It is primarily utilized by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery and preclinical studies for conditions such as non-alcoholic steatohepatitis (NASH) and primary biliary cholangitis (PBC).

Application

• Pharmaceutical R&D: Core active ingredient for developing novel therapeutics targeting metabolic syndromes.
• Non-Alcoholic Steatohepatitis (NASH) Research: Investigational compound for studying mechanisms and treatment of fatty liver disease and fibrosis.
• Primary Biliary Cholangitis (PBC) Therapy Development: Key component in clinical-stage formulations for liver disease management.
• Metabolic Disorder Studies: Used in research on diabetes, dyslipidemia, and other PPAR-mediated pathways.
• Preclinical & Clinical Trial Material: Sourced for manufacturing batches intended for animal studies and human clinical trials.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	Elafibranor (GFT505)
CAS No.	923978-27-2
Molecular Formula	C₂₄H₂₀O₄S
Molecular Weight	404.48 g/mol
Synonyms	GFT-505; GFT505; 2-[2,6-Dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic Acid; 2-Methyl-2-[4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]-2,6-dimethylphenoxy]propanoic Acid; GFT 505; Elafibranorum
EINECS	Contact for details

Quality Control

Our Elafibranor (GFT505) is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support its use in critical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider storing under inert conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	<20 ppm
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.